See additional questions about general topics, Kovaltry® and insurance below.
Questions about Jivi®
Jivi is an extended half-life (EHL) product that offers previously treated adults and adolescents (12 years of age and older) with hemophilia A the potential for fewer infusions. Jivi has a twice weekly starting dose and the potential (based on bleeding episodes) to step up to every 5 days and fine tune. Kogenate FS and Jivi are both manufactured using the same type of cell line. Jivi is not for use in patients under 12 years of age or in previously untreated patients.1 Talk to your doctor to see if Jivi may be right for you.
Yes, Jivi offers unique stepwise dosing with a twice weekly starting dose and, based on bleeding episodes, the potential to step up to every 5 days and fine tune.1
Yes, Jivi clinical studies evaluated efficacy and safety data in previously treated adult and adolescent patients, 12 years of age or older. These studies included 132 on-demand and prophylactic patients*, 48 of whom were previously on Kogenate FS†. Click here to learn more about these patients.1,2
Jivi was approved by the FDA in 2018 based on efficacy and safety data in the treatment and control of bleeding in previously treated adults and adolescents (12 years of age and older) with hemophilia A. Jivi is not for use in patients under 12 years of age or in previously untreated patients.1 Ask your doctor if Jivi is right for you.
Jivi is manufactured using the same type of cell line as Kogenate FS.1,3
Jivi offers patients a twice weekly starting dose and the potential (based on bleeding episodes) to step up to every 5 days and fine tune.1 Talk to your doctor to determine if Jivi is right for you.
Yes, both Jivi and Kogenate FS use the same Vial Adapter reconstitution system.1,3
If your dose requires more than one vial, first reconstitute each vial as described in the Jivi Vial Adapter instructions with the diluent syringe provided. Then, to combine the contents of the vials, use a larger plastic syringe (not provided) to pool the solution into the syringe and administer as usual.
Yes, Jivi is packaged with a 25-gauge butterfly needle.1
Store Jivi under refrigeration at 36°F to 46°F. Do not freeze. Jivi may be stored for a single period of up to 6 months at temperatures up to 77°F. Once stored at room temperature, do not return the product to the refrigerator. The shelf-life then expires after storage at room temperature for 6 months, or after the expiration date on the product vial, whichever is earlier.1 Visit the Jivi website for the full details on storing Jivi.
No, PK testing is not required to transition from Kogenate FS to Jivi; however, if your healthcare provider requests PK testing, Bayer offers patients reimbursement for lab testing through Access Services by Bayer that covers up to $250 in out-of-pocket laboratory testing costs per year.‡§
- Click here to learn how to submit your lab testing reimbursement form.
Visit UnderstandingPK.com to learn about the pharmacokinetic properties of Jivi. This website also includes data from a head-to-head study comparing the pharmacokinetic characteristics of Jivi vs. Eloctate. Talk to your doctor about the PK data in head-to-head studies comparing Jivi vs. Eloctate and Jivi vs. another EHL.
Yes, your healthcare provider can also give you Jivi when you have surgery.1 Speak with your doctor about any upcoming medical procedures.